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Article

Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2008

Seidelmann Sara Bretschger, Kuo Chaoling, Pleskac Nick, Molina Jennifer, Sayers Scott, Li Rong, Zhou Jing, Johnson Pamela, Braun Kathleen, Chan Christina, Teupser Daniel, Breslow Jan L, Wight Thomas N, Tall Alan R, Welch Carrie L

Abstract excerpt

OBJECTIVE: Susceptibility to atherosclerosis is genetically complex, and modifier genes that do not operate via traditional risk factors are largely unknown. A mouse genetics approach can simplify the genetic analysis and provide tools for mechanistic studies. METHODS AND RESULTS: We previously identified atherosclerosis susceptibility QTL (Athsq1) on chromosome 4 acting independently of systemic risk factors. We...

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Identifiers

PMID: 18818413
DOI: 10.1161/ATVBAHA.108.176800
PMCID: PMC2784896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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