Article
Genetic modifiers of atherosclerosis in mice.
Annals of the New York Academy of Sciences - 1 Dec 2001
Smith J D, Dansky H M, Breslow J L
Abstract excerpt
Common atherosclerosis has a genetic component, but it is difficult to determine the specific genes that play a role in atherosclerosis susceptibility in humans. We have used the apoE-deficient mouse as a model system to examine the effects of candidate genes on atherosclerosis as well as to perform genomic experiments to map and isolate other genes giving rise to atherosclerosis susceptibility. We have tested...
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