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Article

Guinea pig model of Mycobacterium tuberculosis latent/dormant infection.

Microbes and infection - 1 Jan 2000

Kashino Suely S, Napolitano Danielle R, Skobe Ziedonis, Campos-Neto Antonio

Abstract excerpt

Although guinea pigs are considered one of the best animal models of tuberculosis, little data exist describing latent or dormant tuberculosis infection in these animals. Here we address this issue using a streptomycin auxotrophic mutant of Mycobacterium tuberculosis. This mutant grows unimpaired in the presence of streptomycin but in its absence shifts to latency/dormancy (lack growth and over-expression of...

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Identifiers

PMID: 18817888
DOI: 10.1016/j.micinf.2008.08.010
PMCID: PMC2743963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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