Article
Latent tuberculosis infection: what we know about its genetic control?
Tuberculosis (Edinburgh, Scotland) - 1 Sept 2014
Kondratieva Tatiana, Azhikina Tatyana, Nikonenko Boris, Kaprelyants Arseny, Apt Alexander
Abstract excerpt
About 90% of all cases of tuberculosis (TB) infection are comprised of latent mycobacterial persistence in the absence of clinical manifestations. In a proportion of latently infected individuals infection eventually reactivates and becomes contagious, seriously influencing epidemiological situation. Mechanisms of Mycobacterium tuberculosis transition to dormancy and TB reactivation are poorly understood, and...
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