Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical strains of Mycobacterium tuberculosis display a wide range of virulence in guinea pigs.

Tuberculosis (Edinburgh, Scotland) - 1 May 2009

Palanisamy Gopinath S, DuTeau Nancy, Eisenach Kathleen D, Cave Donald M, Theus Susan A, Kreiswirth Barry N, Basaraba Randall J, Orme Ian M

Abstract excerpt

Virtually all new tuberculosis vaccine candidates are tested in animals using the laboratory strains H37Rv or Erdman. However, naturally occurring M. tuberculosis infections are caused by strains that are widely different in phenotype and genotype. Very little is known about the characteristics o...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Multiple, Bacterial
Share to Genotype
Share to Guinea Pigs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycobacterium tuberculosis

Share to Species Specificity

Share to Tuberculosis, Pulmonary

Share to Virulence

Source

Identifiers

PMID: 19251482
DOI: 10.1016/j.tube.2009.01.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19251482-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical strains of Mycobacterium tuberculosis display a wide range of virulence in guinea pigs.PMID 19251482Read ↗

Beijing sublineages of Mycobacterium tuberculosis differ in pathogenicity in the guinea pig.Semantic proximity Read ↗

Use of mouse models to study the variability in virulence associated with specific genotypic lineages of Mycobacterium tuberculosis.Semantic proximity Read ↗

Mycobacterium tuberculosis clinical isolates of the Beijing and East-African Indian lineage induce fundamentally different host responses in mice compared to H37RvSemantic proximity Read ↗

Vaccination of guinea pigs using mce operon mutants of Mycobacterium tuberculosis.Semantic proximity Read ↗

Different strains of Mycobacterium tuberculosis cause various spectrums of disease in the rabbit model of tuberculosis.Semantic proximity Read ↗

Accelerated Detection ofMycobacterium tuberculosisGenes Essential for Bacterial Survival in Guinea Pigs, Compared with MiceSemantic proximity Read ↗

Characterization of a novel intratracheal aerosol challenge model of <i>Brucella melitensis</i> in guinea pigsSemantic proximity Read ↗

Virulence, immunopathology and transmissibility of selected strains of Mycobacterium tuberculosis in a murine model.Semantic proximity Read ↗

Mycobacterium tuberculosis strains with the Beijing genotype demonstrate variability in virulence associated with transmission.Semantic proximity Read ↗

A Murine Model of Mycobacterium kansasii Infection Reproducing Necrotic Lung Pathology Reveals Considerable Heterogeneity in Virulence of Clinical IsolatesSemantic proximity Read ↗

Lessons from experimental Mycobacterium tuberculosis infectionsSemantic proximity Read ↗

Clinical isolates of Mycobacterium tuberculosis with different genotypes exhibit distinct host macrophage responses in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.