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Article

Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs.

PloS one - 1 Jan 2013

Chauhan Priyanka, Reddy P Vineel, Singh Ramandeep, Jaisinghani Neetika, Gandotra Sheetal, Tyagi Anil K

Abstract excerpt

BACKGROUND: The failure of Mycobacterium bovis Bacille Calmette-Guérin to impart satisfactory protection against adult pulmonary tuberculosis has necessitated the development of more effective TB vaccines. The assumption that the vaccine strain should be antigenically as similar as possible to the disease causing pathogen has led to the evaluation of M.tuberculosis mutants as candidate tuberculosis vaccines....

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Identifiers

PMID: 24205032
DOI: 10.1371/journal.pone.0077930
PMCID: PMC3799640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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