Article
Unique model of dormant infection for tuberculosis vaccine development.
Clinical and vaccine immunology : CVI - 1 Sept 2006
Kashino Suely S, Ovendale Pamela, Izzo Angelo, Campos-Neto Antonio
Abstract excerpt
Most individuals exposed to Mycobacterium tuberculosis become infected but hinder the infectious process in dormant foci, known as latent tuberculosis. This limited infection usually stimulates strong T-cell responses, which provide lifelong resistance to tuberculosis. However, latent tuberculosis is still poorly understood, particularly because of the lack of a reliable animal model of dormant infection. Here we...
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