Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human granuloma in vitro model, for TB dormancy and resuscitation.

PloS one - 1 Jan 2013

Kapoor Nidhi, Pawar Santosh, Sirakova Tatiana D, Deb Chirajyoti, Warren William L, Kolattukudy Pappachan E

Abstract excerpt

Tuberculosis (TB) is responsible for death of nearly two million people in the world annually. Upon infection, Mycobacterium tuberculosis (Mtb) causes formation of granuloma where the pathogen goes into dormant state and can live for decades before resuscitation to develop active disease when the immune system of the host is weakened and/or suppressed. In an attempt to better understand host-pathogen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotics, Antitubercular
Share to Antibodies, Neutralizing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Granuloma

Share to Host-Pathogen Interactions

Share to Latent Tuberculosis

Share to Lipase

Share to Rifampin

Share to Triglycerides

Source

Open in PubMed Open full text

Identifiers

PMID: 23308269
DOI: 10.1371/journal.pone.0053657
PMCID: PMC3538642

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human granuloma in vitro model, for TB dormancy and resuscitation.PMID 23308269Read ↗

<i>Mycobacterium tuberculosis</i>: success through dormancySemantic proximity Read ↗

A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen.Semantic proximity Read ↗

Tuberculosis: The success tale of less explored dormant Mycobacterium tuberculosisSemantic proximity Read ↗

Langhans giant cells from <i>M. tuberculosis</i>‐induced human granulomas cannot mediate mycobacterial uptakeSemantic proximity Read ↗

Letting Sleeping<i>dos</i>Lie: Does Dormancy Play a Role in Tuberculosis?Semantic proximity Read ↗

The perilipin-like PPE15 protein in Mycobacterium tuberculosis is required for triacylglycerol accumulation under dormancy-inducing conditions.Semantic proximity Read ↗

Human mesenchymal stem cell based intracellular dormancy model of Mycobacterium tuberculosis.Semantic proximity Read ↗

Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of TuberculosisSemantic proximity Read ↗

Understanding the development of tuberculous granulomas: insights into host protection and pathogenesis, a review in humans and animalsSemantic proximity Read ↗

Antimicrobial activity against Mycobacterium tuberculosis under in vitro lipid-rich dormancy conditions.Semantic proximity Read ↗

Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states.Semantic proximity Read ↗

Dissecting host factors that regulate the early stages of tuberculosis infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.