Cellular and genetic mechanisms underlying susceptibility of animal models to tuberculosis infection.

doi:10.1002/0470846526.ch8

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Article

Cellular and genetic mechanisms underlying susceptibility of animal models to tuberculosis infection.

Novartis Foundation symposium - 1 Jan 1998

Orme I

Abstract excerpt

I shall propose a new working hypothesis regarding the immunopathogenesis of tuberculosis infections in the mouse and guinea-pig models of pulmonary disease which differs from the current dogma that the development of caseous and potentially liquefied lesions in the susceptible guinea-pig lung is...

Topics

Animals
Disease Models, Animal
Genetic Predisposition to Disease
Guinea Pigs
Mice
Mice, Inbred Strains
Models, Immunological
Species Specificity
Tuberculosis, Pulmonary

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