Article
ABCB1, ABCC2, SCN1A, SCN2A, GABRA1 gene polymorphisms and drug resistant epilepsy in the Chinese Han population.
Die Pharmazie - 1 Jun 2015
Zhou Luo, Cao Yuze, Long Hongyu, Long Lili, Xu Lin, Liu Zhaoqian, Zhang Ying, Xiao Bo
Abstract excerpt
Drug resistance is common in epilepsy despite multiple available medications. Single nucleotide polymorphisms (SNP) may influence drug efficacy in epilepsy. We therefore aimed to clarify the association between polymorphisms of several controversial SNP loci and drug resistance in Chinese Han epilepsy patients from central China. Among all the 391 recruited subjects, 235 and 156 patients were classified into a...
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