Article
Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population.
Drug metabolism and pharmacokinetics - 1 Jan 2009
Vahab Saadi Abdul, Sen Supratim, Ravindran Nivedita, Mony Sridevi, Mathew Anila, Vijayan Neetha, Nayak Geetha, Bhaskaranand Nalini, Banerjee Moinak, Satyamoorthy Kapaettu
Abstract excerpt
The transmembrane P-glycoprotein that functions as a drug-efflux transporter coded by ATP-binding cassette, subfamily B, member 1/Multidrug Resistance 1 (ABCB1/MDR1) gene is considered relevant to drug absorption and elimination, with access to the central nervous system. Effects of three ABCB1 single nucleotide polymorphisms (SNPs) in genotypic and haplotypic combination have been evaluated in a south Indian...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
