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Article

Nuclear export of Ho endonuclease of yeast via Msn5.

Current genetics - 1 Nov 2008

Bakhrat Anya, Baranes-Bachar Keren, Reshef Dan, Voloshin Olga, Krichevsky Oleg, Raveh Dina

Abstract excerpt

Exportin-5, an evolutionarily conserved nuclear export factor of the beta-karyopherin family, exports phosphorylated proteins and small noncoding RNAs. Msn5, the yeast ortholog, exports primarily phosphorylated cargoes including Ho endonuclease and a number of transcription factors and regulatory proteins. The Msn5-mediated nuclear export of Ho is dependent on phosphorylation of Thr225 by kinases of the DNA...

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PMID: 18807043
DOI: 10.1007/s00294-008-0216-8

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