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Article

Nuclear import of ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system.

The Journal of biological chemistry - 5 May 2006

Bakhrat Anya, Baranes Keren, Krichevsky Oleg, Rom Inna, Schlenstedt Gabriel, Pietrokovski Shmuel, Raveh Dina

Abstract excerpt

Activity of Ho, the yeast mating switch endonuclease, is restricted to a narrow time window of the cell cycle. Ho is unstable and despite being a nuclear protein is exported to the cytoplasm for proteasomal degradation. We report here the molecular basis for the highly efficient nuclear import of Ho and the relation between its short half-life and passage through the nucleus. The Ho nuclear import machinery is...

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Source

Identifiers

PMID: 16507575
DOI: 10.1074/jbc.M600238200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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