Article
The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus.
Nature - 3 Dec 1998
Kaffman A, Rank N M, O'Neill E M, Huang L S, O'Shea E K
Abstract excerpt
The movement of many transcription factors, kinases and replication factors between the nucleus and cytoplasm is important in regulating their activity. In some cases, phosphorylation of a protein regulates its entry into the nucleus; in others, it causes the protein to be exported to the cytopla...
Topics
- Biological Transport
- Cell Nucleus
- Cloning, Molecular
- Cytoplasm
- DNA-Binding Proteins
- Escherichia coli
- Fungal Proteins
- GTP Phosphohydrolases
- Karyopherins
- Mutation
- Nuclear Proteins
- Phosphorylation
- Protein Binding
- Receptors, Cytoplasmic and Nuclear
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- ran GTP-Binding Protein