Article
The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus.
Nature - 3 Dec 1998
Kaffman A, Rank N M, O'Neill E M, Huang L S, O'Shea E K
Abstract excerpt
The movement of many transcription factors, kinases and replication factors between the nucleus and cytoplasm is important in regulating their activity. In some cases, phosphorylation of a protein regulates its entry into the nucleus; in others, it causes the protein to be exported to the cytoplasm. The mechanism by which phosphorylation promotes protein export from the nucleus is poorly understood. Here we...
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