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Article

Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export.

Genes & development - 1 Aug 1999

Krebber H, Taura T, Lee M S, Silver P A

Abstract excerpt

Npl3p, the major mRNA-binding protein of the yeast Saccharomyces cerevisiae shuttles between the nucleus and the cytoplasm. A single amino acid change in the carboxyl terminus of Npl3p (E409 --> K) renders the mutant protein largely cytoplasmic because of a delay in its import into the nucleus. This import defect can be reversed by increasing the intracellular concentration of Mtr10p, the nuclear import receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10444597
DOI: 10.1101/gad.13.15.1994
PMCID: PMC316916

Genes

NES
XPO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export.PMID 10444597Read ↗

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