Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A sensitive array-based assay for identifying multiple TMPRSS2:ERG fusion gene variants.

Nucleic acids research - 1 Nov 2008

Lu Qing, Nunez Esperanza, Lin Chunrun, Christensen Kimberly, Downs Tracy, Carson Dennis A, Wang-Rodriguez Jessica, Liu Yu-Tsueng

Abstract excerpt

Studies of gene fusions in solid tumors are not as extensive as in hematological malignancies due to several technical and analytical problems associated with tumor heterogeneity. Nevertheless, there is a growing interest in the role of fusion genes in common epithelial tumors after the discovery of recurrent TMPRSS2:ETS fusions in prostate cancer. Among all of the reported fusion partners in the ETS gene family,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Oligonucleotide Array Sequence Analysis

Share to Oncogene Proteins, Fusion

Share to Prostatic Neoplasms

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 18794177
DOI: 10.1093/nar/gkn585
PMCID: PMC2582611

Genes

TMPRSS2
ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A sensitive array-based assay for identifying multiple TMPRSS2:ERG fusion gene variants.PMID 18794177Read ↗

Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer.Semantic proximity Read ↗

Fusion in the ETS gene family and prostate cancerSemantic proximity Read ↗

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.Semantic proximity Read ↗

Noninvasive Detection of TMPRSS2:ERG Fusion Transcripts in the Urine of Men with Prostate CancerSemantic proximity Read ↗

Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancerSemantic proximity Read ↗

<i>TMPRSS2:ETV4</i> Gene Fusions Define a Third Molecular Subtype of Prostate CancerSemantic proximity Read ↗

Diversity of TMPRSS2-ERG fusion transcripts in the human prostate.Semantic proximity Read ↗

[TMPRSS2-ETS gene fusion in prostate cancer].Semantic proximity Read ↗

Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer.Semantic proximity Read ↗

ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor.Semantic proximity Read ↗

Transcriptomes of Prostate Cancer with TMPRSS2:ERG and Other ETS FusionsSemantic proximity Read ↗

Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation–Mass Spectrometry AssaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.