Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>TMPRSS2:ETV4</i> Gene Fusions Define a Third Molecular Subtype of Prostate Cancer

1 Apr 2006

Abstract excerpt

Although common in hematologic and mesenchymal malignancies, recurrent gene fusions have not been well characterized in epithelial carcinomas. Recently, using a novel bioinformatic approach, we identified recurrent gene fusions between TMPRSS2 and the ETS family members ERG or ETV1 in the majority of prostate cancers. Here, we interrogated the expression of all ETS family members in prostate cancer profiling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Molecular Biology Techniques and Applications
Share to Prostate Cancer Treatment and Research
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16585160
DOI: 10.1158/0008-5472.can-06-0168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>TMPRSS2:ETV4</i> Gene Fusions Define a Third Molecular Subtype of Prostate CancerPMID 16585160Read ↗

Recurrent Fusion of <i>TMPRSS2</i> and ETS Transcription Factor Genes in Prostate CancerSemantic proximity Read ↗

Distinct genomic aberrations associated with ERG rearranged prostate cancerSemantic proximity Read ↗

[TMPRSS2-ETS gene fusion in prostate cancer].Semantic proximity Read ↗

The Discovery of Common Recurrent Transmembrane Protease Serine 2 (TMPRSS2)-Erythroblastosis Virus E26 Transforming Sequence (ETS) Gene Fusions in Prostate CancerSemantic proximity Read ↗

ETS fusion genes in prostate cancerSemantic proximity Read ↗

ETS Gene Fusions in Prostate Cancer: From Discovery to Daily Clinical PracticeSemantic proximity Read ↗

A Fluorescence <i>In situ</i> Hybridization Screen for E26 Transformation–Specific Aberrations: Identification of DDX5-ETV4 Fusion Protein in Prostate CancerSemantic proximity Read ↗

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.Semantic proximity Read ↗

<i>TMPRSS2:ERG</i> Fusion by Translocation or Interstitial Deletion Is Highly Relevant in Androgen-Dependent Prostate Cancer, But Is Bypassed in Late-Stage Androgen Receptor–Negative Prostate CancerSemantic proximity Read ↗

The discovery and application of gene fusions in prostate cancer.Semantic proximity Read ↗

ETS gene fusions in prostate cancerSemantic proximity Read ↗

[Dangerous liaisons in prostate cancer. Clinical and biological implications of recurrent gene fusions].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.