Article
[TMPRSS2-ETS gene fusion in prostate cancer].
Der Urologe. Ausg. A - 1 Jul 2007
Perner S, Schmidt F H, Hofer M D, Kuefer R, Rubin M
Abstract excerpt
BACKGROUND: Recurrent chromosomal rearrangements have not been well characterized in common carcinomas. Using a novel bioinformatics approach, our group recently described a novel gene fusion in PCa. This fusion involves the androgen-regulated gene TMPRSS2 and so far three members of the ETS family of transcription factors already described as rearranged in the Ewing's family of tumors. By analogy, fusion status...
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