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Transcriptomes of Prostate Cancer with TMPRSS2:ERG and Other ETS Fusions

20 Sept 2022

Abstract excerpt

The most common somatic event in primary prostate cancer is a fusion between the androgen-related TMPRSS2 gene and the ERG oncogene. Tumors with these fusions, which occur early in carcinogenesis, have a distinctive etiology. A smaller subset of other tumors harbor fusions between TMPRSS2 and members of the ETS transcription factor family other than ERG. To assess the genomic similarity of tumors with non-ERG ETS...

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PMID: 36125519
DOI: 10.1158/1541-7786.mcr-22-0446

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