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Article

Noninvasive Detection of TMPRSS2:ERG Fusion Transcripts in the Urine of Men with Prostate Cancer

1 Oct 2006

Abstract excerpt

We recently reported the identification of recurrent gene fusions in the majority of prostate cancers involving the 5' untranslated region of the androgen-regulated gene TMPRSS2 and the ETS family members ERG, ETV1, and ETV4. Here we report the noninvasive detection of these gene fusions in the urine of patients with clinically localized prostate cancer. By quantitative polymerase chain reaction, we assessed the...

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PMID: 17059688
DOI: 10.1593/neo.06625

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Noninvasive Detection of TMPRSS2:ERG Fusion Transcripts in the Urine of Men with Prostate CancerPMID 17059688Read ↗

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