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Article

Structure of selenophosphate synthetase essential for selenium incorporation into proteins and RNAs.

Journal of molecular biology - 6 Feb 2009

Itoh Yuzuru, Sekine Shun-ichi, Matsumoto Eiko, Akasaka Ryogo, Takemoto Chie, Shirouzu Mikako, Yokoyama Shigeyuki

Abstract excerpt

Selenophosphate synthetase (SPS) catalyzes the activation of selenide with adenosine 5'-triphosphate (ATP) to generate selenophosphate, the essential reactive selenium donor for the formation of selenocysteine (Sec) and 2-selenouridine residues in proteins and RNAs, respectively. Many SPS are themselves Sec-containing proteins, in which Sec replaces Cys in the catalytically essential position (Sec/Cys). We solved...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18773910
DOI: 10.1016/j.jmb.2008.08.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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