Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure of a tRNA-dependent kinase essential for selenocysteine decoding.

Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2009

Araiso Yuhei, Sherrer R Lynn, Ishitani Ryuichiro, Ho Joanne M L, Söll Dieter, Nureki Osamu

Abstract excerpt

Compared to bacteria, archaea and eukaryotes employ an additional enzyme for the biosynthesis of selenocysteine (Sec), the 21(st) natural amino acid (aa). An essential RNA-dependent kinase, O-phosphoseryl-tRNA(Sec) kinase (PSTK), converts seryl-tRNA(Sec) to O-phosphoseryl-tRNA(Sec), the immediate precursor of selenocysteinyl-tRNA(Sec). The sequence of Methanocaldococcus jannaschii PSTK (MjPSTK) suggests an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Archaeal Proteins
Share to Crystallization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Crystallography, X-Ray

Share to Genetic Complementation Test

Share to Protein Multimerization

Share to Protein Serine-Threonine Kinases

Share to RNA, Transfer, Amino Acyl

Share to Selenocysteine

Source

Open in PubMed Open full text

Identifiers

PMID: 19805283
DOI: 10.1073/pnas.0908861106
PMCID: PMC2752577

Genes

PSTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure of a tRNA-dependent kinase essential for selenocysteine decoding.PMID 19805283Read ↗

C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA(Sec).Semantic proximity Read ↗

Characterization and evolutionary history of an archaeal kinase involved in selenocysteinyl-tRNA formation.Semantic proximity Read ↗

Modeling the tertiary interactions in the eukaryotic selenocysteine tRNA.Semantic proximity Read ↗

Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation.Semantic proximity Read ↗

Structure of selenophosphate synthetase essential for selenium incorporation into proteins and RNAs.Semantic proximity Read ↗

The length of the aminoacyl-acceptor stem of the selenocysteine-specific tRNA(Sec) of Escherichia coli is the determinant for binding to elongation factors SELB or Tu.Semantic proximity Read ↗

Formation of a Ternary Complex for Selenocysteine Biosynthesis in Bacteria.Semantic proximity Read ↗

Structure of the human KEOPS/tRNA complex and characterization of pathogenic variants responsible for the Galloway Mowat syndromeSemantic proximity Read ↗

Identification of the amino acid residues essential for proteolytic activity in an archaeal signal peptide peptidase.Semantic proximity Read ↗

Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification.Semantic proximity Read ↗

Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.Semantic proximity Read ↗

Structure of prokaryotic SECIS mRNA hairpin and its interaction with elongation factor SelB.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.