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Article

Regulation of selenocysteine incorporation into the selenium transport protein, selenoprotein P.

The Journal of biological chemistry - 5 Sept 2014

Shetty Sumangala P, Shah Ravi, Copeland Paul R

Abstract excerpt

Selenoproteins are unique as they contain selenium in their active site in the form of the 21st amino acid selenocysteine (Sec), which is encoded by an in-frame UGA stop codon. Sec incorporation requires both cis- and trans-acting factors, which are known to be sufficient for Sec incorporation in vitro, albeit with low efficiency. However, the abundance of the naturally occurring selenoprotein that contains 10...

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Identifiers

PMID: 25063811
DOI: 10.1074/jbc.M114.590430
PMCID: PMC4155693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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