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Article

Characterization and evolutionary history of an archaeal kinase involved in selenocysteinyl-tRNA formation.

Nucleic acids research - 1 Mar 2008

Sherrer R Lynn, O'Donoghue Patrick, Söll Dieter

Abstract excerpt

Selenocysteine (Sec)-decoding archaea and eukaryotes employ a unique route of Sec-tRNA(Sec) synthesis in which O-phosphoseryl-tRNA(Sec) kinase (PSTK) phosphorylates Ser-tRNA(Sec) to produce the O-phosphoseryl-tRNA(Sec) (Sep-tRNA(Sec)) substrate that Sep-tRNA:Sec-tRNA synthase (SepSecS) converts to Sec-tRNA(Sec). This study presents a biochemical characterization of Methanocaldococcus jannaschii PSTK, including...

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Identifiers

PMID: 18174226
DOI: 10.1093/nar/gkm1134
PMCID: PMC2275090

Genes

PSTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization and evolutionary history of an archaeal kinase involved in selenocysteinyl-tRNA formation.PMID 18174226Read ↗

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