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Article

Composition and evolution of the vertebrate and mammalian selenoproteomes.

PloS one - 1 Jan 2012

Mariotti Marco, Ridge Perry G, Zhang Yan, Lobanov Alexei V, Pringle Thomas H, Guigo Roderic, Hatfield Dolph L, Gladyshev Vadim N

Abstract excerpt

BACKGROUND: Selenium is an essential trace element in mammals due to its presence in proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing protein genes, and mouse and rat genomes for 24. METHODOLOGY/PRINCIPAL FINDINGS: We characterized the selenoproteomes of 44 sequenced vertebrates by applying gene prediction and phylogenetic reconstruction methods, supplemented with the...

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Identifiers

PMID: 22479358
DOI: 10.1371/journal.pone.0033066
PMCID: PMC3316567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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