Article
In search of causal variants: refining disease association signals using cross-population contrasts.
BMC genetics - 29 Aug 2008
Saccone Nancy L, Saccone Scott F, Goate Alison M, Grucza Richard A, Hinrichs Anthony L, Rice John P, Bierut Laura J
Abstract excerpt
BACKGROUND: Genome-wide association (GWA) using large numbers of single nucleotide polymorphisms (SNPs) is now a powerful, state-of-the-art approach to mapping human disease genes. When a GWA study detects association between a SNP and the disease, this signal usually represents association with...
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