Article
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.
Genetic epidemiology - 1 May 2012
Chen Li-Shiun, Saccone Nancy L, Culverhouse Robert C, Bracci Paige M, Chen Chien-Hsiun, Dueker Nicole, Han Younghun, Huang Hongyan, Jin Guangfu, Kohno Takashi, Ma Jennie Z, Przybeck Thomas R, Sanders Alan R, Smith Jennifer A, Sung Yun Ju, Wenzlaff Angie S, Wu Chen, Yoon Dankyu, Chen Ying-Ting, Cheng Yu-Ching, Cho Yoon Shin, David Sean P, Duan Jubao, Eaton Charles B, Furberg Helena, Goate Alison M, Gu Dongfeng, Hansen Helen M, Hartz Sarah, Hu Zhibin, Kim Young Jin, Kittner Steven J, Levinson Douglas F, Mosley Thomas H, Payne Thomas J, Rao D C, Rice John P, Rice Treva K, Schwantes-An Tae-Hwi, Shete Sanjay S, Shi Jianxin, Spitz Margaret R, Sun Yan V, Tsai Fuu-Jen, Wang Jen C, Wrensch Margaret R, Xian Hong, Gejman Pablo V, He Jiang, Hunt Steven C, Kardia Sharon L, Li Ming D, Lin Dongxin, Mitchell Braxton D, Park Taesung, Schwartz Ann G, Shen Hongbing, Wiencke John K, Wu Jer-Yuarn, Yokota Jun, Amos Christopher I, Bierut Laura J
Abstract excerpt
Recent meta-analyses of European ancestry subjects show strong evidence for association between smoking quantity and multiple genetic variants on chromosome 15q25. This meta-analysis extends the examination of association between distinct genes in the CHRNA5-CHRNA3-CHRNB4 region and smoking quantity to Asian and African American populations to confirm and refine specific reported associations. Association results...
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