Article
Polymorphisms of EDNRB, ATG, and ACE genes in salt-sensitive hypertension.
Canadian journal of physiology and pharmacology - 1 Aug 2008
Caprioli Jessica, Mele Caterina, Mossali Chiara, Gallizioli Laura, Giacchetti Gilberta, Noris Marina, Remuzzi Giuseppe, Benigni Ariela
Abstract excerpt
Almost 50% of hypertensive individuals manifest blood pressure changes in response to salt depletion or repletion and are termed "salt sensitive" (SS). Blunted activity of the endothelin (ET) system and the renin-angiotensin-aldosterone system (RAAS) have been reported as possible mechanisms contributing to salt sensitivity. Data are available that endothelin receptor subtype B (ETBR)-deficient rats develop...
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