Article
A polymorphism in the endothelin-A receptor gene is linked to baroreflex sensitivity.
Journal of hypertension - 1 Nov 2005
Ormezzano Olivier, Poirier Odette, Mallion Jean-Michel, Nicaud Viviane, Amar Jacques, Chamontin Bernard, Mounier-Véhier Claire, François Patrice, Cambien François, Baguet Jean Philippe
Abstract excerpt
BACKGROUND: The baroreflex plays an essential role in regulating the cardiovascular system. However, very few studies have focused on the links between genetic polymorphisms and baroreflex sensitivity (BRS). METHODS: A total of 146 hypertensive individuals who had never been treated, and 105 healthy individuals (controls) were included in the study. The genotypes of 17 polymorphisms of 11 genes involved in the...
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