Article
Identification of a polymorphic glutamic acid stretch in the alpha2B-adrenergic receptor and lack of linkage with essential hypertension.
American journal of hypertension - 1 Sept 1999
Baldwin C T, Schwartz F, Baima J, Burzstyn M, DeStefano A L, Gavras I, Handy D E, Joost O, Martel T, Manolis A, Nicolaou M, Bresnahan M, Farrer L, Gavras H
Abstract excerpt
Essential hypertension, a clinically significant elevation in blood pressure with no recognizable cause, is believed to be attributable to the collective effect of genetic predisposing factors in combination with specific environmental factors, such as diet and stress. Of the genetic causes, genes coding for proteins involved in blood pressure regulation, such as the alpha- and beta-adrenergic receptors, are...
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