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Article

Systematic screening of type B human natriuretic peptide receptor gene polymorphisms and association with essential hypertension.

Journal of human hypertension - 1 Jul 2001

Rahmutula D, Nakayama T, Soma M, Sato M, Izumi Y, Kanmatsuse K, Ozawa Y

Abstract excerpt

C-type natriuretic peptide (CNP) dilates arteries, lowers blood pressure and inhibits proliferation of vascular smooth muscle cells via the type B natriuretic peptide receptor (NPRB). The CNP-NPRB system may play a crucial role in the development of cardiovascular disease. We recently determined the structure of the human NPRB gene. In the present study, our objectives are to identify the polymorphisms of the...

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Source

Identifiers

PMID: 11464256
DOI: 10.1038/sj.jhh.1001199

Genes

CNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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