Article
Renin-angiotensin-aldosterone system and G-protein beta-3 subunit gene polymorphisms in salt-sensitive essential hypertension.
Journal of human hypertension - 1 Mar 2003
Pamies-Andreu E, Ramirez-Lorca R, Stiefel García-Junco P, Muñiz-Grijalbo O, Vallejo-Maroto I, Garcia Morillo S, Miranda-Guisado M L, Ortíz J V, Carneado de la Fuente J
Abstract excerpt
Approximately 50% of hypertensive patients are salt sensitive (they increase their Blood Pressure in response to sodium intake or volume expansion). Mechanisms underlying salt sensitivity are not completely elucidated although there is evidence that they may be genetically determined. The aim of this study is to establish the relation among some genetic polymorphisms of the renin-angiotensin system (RAAS) and the...
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