Article
Role of the alpha2B-adrenergic receptor in the development of salt-induced hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999
Makaritsis K P, Handy D E, Johns C, Kobilka B, Gavras I, Gavras H
Abstract excerpt
Salt sensitivity is a common trait in patients with essential hypertension and seems to have both an inherited and an acquired component (eg, is influenced by aging and renal insufficiency). Experimental evidence suggests that salt loading induces hypertension via a neurogenic mechanism mediated...
Topics
- Aging
- Animals
- Base Sequence
- Blood Pressure Determination
- Body Weight
- Creatinine
- Data Interpretation, Statistical
- Genetic Predisposition to Disease
- Genotype
- Hypertension
- Male
- Mice
- Molecular Sequence Data
- Monitoring, Physiologic
- Nephrectomy
- Organ Size
- Polymerase Chain Reaction
- Receptors, Adrenergic, alpha-2