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Article

Role of the alpha2B-adrenergic receptor in the development of salt-induced hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999

Makaritsis K P, Handy D E, Johns C, Kobilka B, Gavras I, Gavras H

Abstract excerpt

Salt sensitivity is a common trait in patients with essential hypertension and seems to have both an inherited and an acquired component (eg, is influenced by aging and renal insufficiency). Experimental evidence suggests that salt loading induces hypertension via a neurogenic mechanism mediated by the alpha2-adrenergic receptors (alpha2-AR). To explore the alpha2-AR subtype involved in this mechanism, we studied...

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Identifiers

PMID: 9931075
DOI: 10.1161/01.hyp.33.1.14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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