Article
Renin-angiotensin system genetic polymorphisms and salt sensitivity in essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 2000
Giner V, Poch E, Bragulat E, Oriola J, González D, Coca A, De La Sierra A
Abstract excerpt
We evaluated the association between salt-sensitive hypertension and 3 different genetic polymorphisms of the renin-angiotensin system. Fifty patients with essential hypertension were classified as salt sensitive or salt resistant, depending on the presence or absence of a significant increase (P<0.05) in 24-hour ambulatory mean blood pressure (BP) after high salt intake. The insertion/deletion (I/D)...
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