Article
Epigenetic dysregulation in systemic lupus erythematosus.
Autoimmunity - 1 Jun 2014
Liu Aijing, La Cava Antonio
Abstract excerpt
Systemic lupus erythematosus (SLE) is a prototypical systemic autoimmune disease that affects multiple organs and is characterized by episodic flares and elevated morbidity. The etiology of SLE is only partly known. In this context, recent attention has been paid to the importance of environmentally induced epigenetic modifications as significant contributors to the disease pathogenesis in genetically predisposed...
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