Article
MAGI2 genetic variation and inflammatory bowel disease.
Inflammatory bowel diseases - 1 Jan 2009
McGovern Dermot P B, Taylor Kent D, Landers Carol, Derkowski Carrie, Dutridge Deb, Dubinsky Marla, Ippoliti Andy, Vasiliauskas Eric, Mei Ling, Mengesha Emebet, King Lily, Pressman Sheila, Targan Stephan R, Rotter Jerome I
Abstract excerpt
BACKGROUND: Despite recent advances the majority of inflammatory bowel disease (IBD) susceptibility 'genes' remain undiscovered. Recent data suggest that autoimmune conditions may 'share' susceptibility loci. Epidemiological evidence indicates an association between celiac disease and IBD and both conditions demonstrate increased gut permeability. MAGI2, recently implicated in ulcerative colitis (UC) and celiac...
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