Article
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
Nature genetics - 1 Dec 2009
Asano Kouichi, Matsushita Tomonaga, Umeno Junji, Hosono Naoya, Takahashi Atsushi, Kawaguchi Takahisa, Matsumoto Takayuki, Matsui Toshiyuki, Kakuta Yoichi, Kinouchi Yoshitaka, Shimosegawa Tooru, Hosokawa Masayo, Arimura Yoshiaki, Shinomura Yasuhisa, Kiyohara Yutaka, Tsunoda Tatsuhiko, Kamatani Naoyuki, Iida Mitsuo, Nakamura Yusuke, Kubo Michiaki
Abstract excerpt
Ulcerative colitis is one of the principal forms of inflammatory bowel disease with complex manifestations. Although previous studies have indicated that there is a genetic contribution to the pathogenesis of ulcerative colitis, the genes influencing susceptibility to the disease have not been fully determined. To identify genetic factors conferring risk of ulcerative colitis, here we conducted a two-stage...
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