Article
Genetic susceptibility in IBD: overlap between ulcerative colitis and Crohn's disease.
Inflammatory bowel diseases - 1 Feb 2013
Doecke James D, Simms Lisa A, Zhao Zhen Zhen, Huang Ning, Hanigan Katherine, Krishnaprasad Krupa, Roberts Rebecca L, Andrews Jane M, Mahy Gillian, Bampton Peter, Lewindon Peter, Florin Timothy, Lawrance Ian C, Gearry Richard B, Montgomery Grant W, Radford-Smith Graham L
Abstract excerpt
BACKGROUND: The etiology of ulcerative colitis (UC) and Crohn's disease (CD) involves both genetic and environmental components. Multiple UC and CD susceptibility genes have been identified through genome-wide association studies and subsequent meta-analyses. These studies have also highlighted the presence of genes common to both diseases, and shared with several other autoimmune disorders. The aim of this study...
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