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Article

Genetic variation and expression levels of tight junction genes identifies association between MAGI3 and inflammatory bowel disease.

BMC gastroenterology - 25 May 2017

Norén Elisabeth, Almer Sven, Söderman Jan

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) is associated with increased intestinal permeability, which involves paracellular passage regulated through tight junctions (TJ). The aim of the study was to investigate single nucleotide polymorphisms (SNP) located in genes encoding interacting TJ proteins and corresponding expressions, in relation to IBD. METHODS: Allelic associations between TJ-related genes (F11R,...

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Topics

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Share to Cell Adhesion Molecules
Share to Cell Adhesion Molecules, Neuronal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colitis, Ulcerative

Share to Guanylate Kinases

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to PTEN Phosphohydrolase

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Share to Zonula Occludens-1 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 28545409
DOI: 10.1186/s12876-017-0620-y
PMCID: PMC5445404

Genes

MAGI3
MAGI2
PTEN
PTPN22
TJP1
MAGI1
PARD3

Provenance

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