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Article

The Ku complex in silencing the cryptic mating-type loci of Saccharomyces cerevisiae.

Genetics - 1 Oct 2008

Patterson Erin E, Fox Catherine A

Abstract excerpt

Sir1 establishes transcriptional silencing at the cryptic mating-type loci HMR and HML (HM loci) by recruiting the three other Sir proteins, Sir2, -3, and -4, that function directly in silenced chromatin. However, SIR1-independent mechanisms also contribute to recruiting the Sir2-4 proteins to the HM loci. A screen to elucidate SIR1-independent mechanisms that establish HMR silencing identified a mutation in...

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Identifiers

PMID: 18716325
DOI: 10.1534/genetics.108.091710
PMCID: PMC2567379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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