Article
The redox environment in the mitochondrial intermembrane space is maintained separately from the cytosol and matrix.
The Journal of biological chemistry - 24 Oct 2008
Hu Jingjing, Dong Lixue, Outten Caryn E
Abstract excerpt
Redox control in the mitochondrion is essential for the proper functioning of this organelle. Disruption of mitochondrial redox processes contributes to a host of human disorders, including cancer, neurodegenerative diseases, and aging. To better characterize redox control pathways in this organelle, we have targeted a green fluorescent protein-based redox sensor to the intermembrane space (IMS) and matrix of...
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