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Article

Cytosolic Fe-S Cluster Protein Maturation and Iron Regulation Are Independent of the Mitochondrial Erv1/Mia40 Import System.

The Journal of biological chemistry - 13 Nov 2015

Ozer Hatice K, Dlouhy Adrienne C, Thornton Jeremy D, Hu Jingjing, Liu Yilin, Barycki Joseph J, Balk Janneke, Outten Caryn E

Abstract excerpt

The sulfhydryl oxidase Erv1 partners with the oxidoreductase Mia40 to import cysteine-rich proteins in the mitochondrial intermembrane space. In Saccharomyces cerevisiae, Erv1 has also been implicated in cytosolic Fe-S protein maturation and iron regulation. To investigate the connection between Erv1/Mia40-dependent mitochondrial protein import and cytosolic Fe-S cluster assembly, we measured Mia40 oxidation and...

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Identifiers

PMID: 26396185
DOI: 10.1074/jbc.M115.682179
PMCID: PMC4646028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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