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Article

Cytosolic thioredoxin system facilitates the import of mitochondrial small Tim proteins.

EMBO reports - 1 Oct 2012

Durigon Romina, Wang Qi, Ceh Pavia Efrain, Grant Chris M, Lu Hui

Abstract excerpt

Thiol-disulphide redox regulation has a key role during the biogenesis of mitochondrial intermembrane space (IMS) proteins. Only the Cys-reduced form of precursor proteins can be imported into mitochondria, which is followed by disulphide bond formation in the mitochondrial IMS. In contrast to the wealth of knowledge on the oxidation process inside mitochondria, little is known about how precursors are maintained...

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Source

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Identifiers

PMID: 22878414
DOI: 10.1038/embor.2012.116
PMCID: PMC3463972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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