Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotyping beta-globin gene mutations on copolymer-coated glass slides with the ligation detection reaction.

Clinical chemistry - 1 Oct 2008

Battistella Stefania, Damin Francesco, Chiari Marcella, Delgrosso Kathleen, Surrey Saul, Fortina Paolo, Ferrari Maurizio, Cremonesi Laura

Abstract excerpt

BACKGROUND: Methods are needed to analyze small amounts of samples for variation in disease-causing genes. One means is to couple the sensitivity and multiplexing capability of the ligation detection reaction (LDR) with the use of simple glass slides specifically functionalized with a novel polymer coating to enhance sensitivity. METHODS: We developed an array-based genotyping assay based on glass slides coated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Primers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HBB gene

Share to Genotype

Share to Globins

Share to Mutation

Share to Nucleic Acid Hybridization

Share to Oligonucleotide Array Sequence Analysis

Source

Identifiers

PMID: 18703765
DOI: 10.1373/clinchem.2008.107870

Genes

HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotyping beta-globin gene mutations on copolymer-coated glass slides with the ligation detection reaction.PMID 18703765Read ↗

Identification of single-nucleotide polymorphisms by the oligonucleotide ligation reaction: a DNA biosensor for simultaneous visual detection of both alleles.Semantic proximity Read ↗

Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay.Semantic proximity Read ↗

Genotyping by ligation assays.Semantic proximity Read ↗

Development of a fibrous DNA chip for cost-effective β-thalassemia genotyping.Semantic proximity Read ↗

SNP genotyping by multiplexed solid-phase amplification and fluorescent minisequencing.Semantic proximity Read ↗

Genotyping of mutation in the beta-globin gene using DNA microarrays.Semantic proximity Read ↗

High-throughput microtiter well-based chemiluminometric genotyping of 15 HBB gene mutations in a dry-reagent format.Semantic proximity Read ↗

A low-cost hydrogel chip for SNP typing by the incorporation of Cy5-dCTP into label-free allele-specific probes hybridizing to gel-immobilized targets.Semantic proximity Read ↗

New labelling technology for molecular probes applied to the ligation detection reaction-universal array system.Semantic proximity Read ↗

Detection of multiple SNPs in numerous samples with polyacrylamide gel-based microarray.Semantic proximity Read ↗

Detection of mutations by fill-in ligation reaction with enzyme-linked immunosorbent assay for rapid medical diagnosis.Semantic proximity Read ↗

Block copolymer-oligonucleotide conjugates for genotyping on microarrays.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.