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Article

New labelling technology for molecular probes applied to the ligation detection reaction-universal array system.

Molecular biotechnology - 1 Jan 2011

Lauri Andrea, Chessa Stefania, Raschetti Marta, Castiglioni Bianca, Mariani Paola, Caetano Alexandre R

Abstract excerpt

The ligation detection reaction (LDR) associated with universal arrays (UA) uses a fluorescently labelled probe (DP) and a Zip Code-extended probe to detect single nucleotide polymorphisms in DNA target sequences. When used for genotyping, the LDR-UA technique uses two DPs, each specific to an allele and labelled with a different fluorophore. The fluorescent signals are processed to calculate the genotype. The...

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PMID: 20577831
DOI: 10.1007/s12033-010-9305-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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