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Article

High-throughput microtiter well-based chemiluminometric genotyping of 15 HBB gene mutations in a dry-reagent format.

Clinical chemistry - 1 Mar 2007

Glynou Kyriaki, Kastanis Petros, Boukouvala Sotiria, Tsaoussis Vassilis, Ioannou Penelope C, Christopoulos Theodore K, Traeger-Synodinos Joanne, Kanavakis Emmanuel

Abstract excerpt

BACKGROUND: Hemoglobinopathies are the most common inherited diseases worldwide. Various methods for genotyping of hemoglobin, beta (HBB) gene mutations have been reported, but there is need for a high sample-throughput, cost-effective method for simultaneous screening of several mutations. We report a method that combines the high detectability and dynamic range of chemiluminescence with the high...

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PMID: 17259233
DOI: 10.1373/clinchem.2006.077776

Genes

HBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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