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Article

Psychological functioning in persons considering genetic counseling and testing for Li–Fraumeni syndrome

1 Aug 2008

Abstract excerpt

OBJECTIVE: Li-Fraumeni syndrome (LFS) confers an increased risk of multiple types of cancer in both children and adults. Clinical genetic testing for deleterious germline p53 gene mutations can identify most LFS-affected families. We evaluated factors associated with cancer-specific distress and perceived self-efficacy in coping with a positive genetic test result among persons at risk of having deleterious p53...

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PMID: 18688785
DOI: 10.1002/pon.1352

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