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Article

Parent decision-making around the genetic testing of children for germline TP53 mutations.

Cancer - 15 Jan 2015

Alderfer Melissa A, Zelley Kristin, Lindell Robert B, Novokmet Ana, Mai Phuong L, Garber Judy E, Nathan Deepika, Scollon Sarah, Chun Nicolette M, Patenaude Andrea F, Ford James M, Plon Sharon E, Schiffman Joshua D, Diller Lisa R, Savage Sharon A, Malkin David, Ford Carol A, Nichols Kim E

Abstract excerpt

BACKGROUND: Li-Fraumeni syndrome is a rare genetic cancer predisposition syndrome caused by germline TP53 mutations. Up to 20% of mutation carriers develop cancer during childhood. The benefits of TP53 mutation testing of children are a matter of debate and knowledge of parent decision-making around such testing is limited. The current study examined how parents make decisions regarding TP53 testing for their...

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PMID: 25223899
DOI: 10.1002/cncr.29027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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