Article
Health Behavior and Cancer Prevention among Adults with Li-Fraumeni Syndrome and Relatives in Germany-A Cohort Description.
Current oncology (Toronto, Ont.) - 15 Oct 2022
Nees Juliane, Kiermeier Senta, Struewe Farina, Keymling Myriam, Maatouk Imad, Kratz Christian P, Schott Sarah
Abstract excerpt
Li-Fraumeni-syndrome (LFS) is a rare, highly penetrant cancer predisposition syndrome (CPS) caused by pathogenic variants (PVs) in TP53. Physical activity (PA) and a Mediterranean diet lead to cancer reduction or survival benefits and increased quality of life (QoL), but this is yet unstudied among LFS. TP53 PV carriers (PVC) and their relatives were questioned on dietary patterns (Mediterranean Diet Adherence...
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