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Article

Families' and health care professionals' attitudes towards Li-Fraumeni syndrome testing in children: A systematic review.

Clinical genetics - 1 Jan 2019

Warby Meera, Wakefield Claire E, Vetsch Janine, Tucker Katherine M

Abstract excerpt

Li-Fraumeni syndrome (LFS) is a highly penetrant cancer predisposition syndrome caused by germline TP53 mutations. Genetic testing is not routinely offered in asymptomatic children at risk of the condition as the benefits are debatable and the attitudes of families and health care professionals (HCPs) may vary. This review assessed the attitudes of families and HCPs towards offering genetic testing to children...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30191952
DOI: 10.1111/cge.13442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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